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KMID : 0986520100100040245
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Korean Journal of Endoscrine Surgery
2010 Volume.10 No. 4 p.245 ~ p.248
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The Characteristics and Strategy of Treatment for Non-diagnostic Thyroid Fine-needle Aspiration Cytology
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Kim Ju-Yeon
Jung Eun-Jung
Jeong Sang-Ho
Ju Young-Tae
Jeong Chi-Young
Lee Young-Joon
Hong Soon-Chan
Choi Sang-Kyung
Ha Woo-Song
Park Soon-Tae
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Abstract
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Purpose: The management of non-diagnostic fine needle aspiration biopsy of thyroid nodules has been a dilemma. The purposes of this study were to analyze the characteristics and the results of follow up of non-diagnostic aspirates and to evaluate the management strategy.
Methods: A retrospective review was conducted on the patients who underwent fine-needle aspiration of thyroid nodules that were found on a health examination. The patients’ records were assessed for the demographics, the ultrasound findings and the pathologic findings.
Results: The initial non-diagnostic rate was 35%. The nodule size (≤10 mm) and cystic nodule were related to a high rate of non-diagnostic results. The common causes of non-diagnostic results by pathologic description were reducedcellularity (59.3%) and blood (28.2%). Among the 62 initially non-diagnosed patients, 2 patients were confirmed to have malignancy and 32 patients (51.6%) were lost from follow-up. Reaspiration was performed in 18 patients and 6 patients still resulted non-diagnostic aspirates.
Conclusion: Nodule size and cystic nodule were associated with a high rate of non-diagnostic results. Non-diagnostic results of thyroid nodules may be associated with a relatively high frequency of follow up loss, and non-diagnostic results may be associated with a probability of malignancy. So, non-diagnostic results should not be considered just benign, and clinicians should recommend a repeat exam for such patients.
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KEYWORD
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Thyroid nodules, Fine-needle aspiration cytology, Non-diagnotic
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